The Palace is made of two contiguous buildings that, even though were made in different eras, show a homogeneous arrangement of the internal spaces, terraces and gardens. The first core of the Palace was built at the beginning of the Seventeenth Century upon commission by the Galloppi family. Towards the end of the Eighteenth Century it passed on to the Santovetti and finally to the Volpi from Misurata.
The building was enlarged at the end of the Seventeenth Century by Alessandro Specchi, who decided to decorate it in a late Baroque style, ending in the decorated cornice that splits the façade today.
The Palace also includes a structure built on via Quattro Fontane, which was merged into the original core by Armando Basini in1926 – 28. The smooth plaster of the facades is alternated to the basements in travertine stone, interrupted here and there by portals framed by pilasters an tympanums with noble coats of arm.